Malaria remains a serious global health issue, infecting over 350 million people annually and killing over 1 million people, most in Africa. It is transmitted through the bites of infected female Anopheles mosquitoes. While some cases still occur in the United States, transmitted by two mosquito species, the largest burden is in developing countries where poor, vulnerable groups like children and pregnant women are most at risk due to limited access to prevention and treatment. Proper use of insecticide-treated bed nets and antimalarial drugs can effectively reduce transmission and save lives.